abstract：BACKGROUND AND OBJECTIVE:To determine the prevalence of health care workers (HCW) susceptibility to varicella zoster virus (VZV). As a secondary objective, we describe the immunogenicity and reactogenicity of the vaccine. SUBJECTS AND METHODS:A multicenter analytic cross-sectional study was conducted in 5 hospitals in...

journal_title：Medicina clinica

authors： García-Basteiro AL,Bayas JM,Campins M,Torres M,Serra C,Varela P,Barbé E,Vidal J,Grupo de Estudio de la Varicela en Hospitales de Cataluña.

更新日期：2011-09-24 00:00:00

abstract：:Negative-pressure wound therapy (NPWT) is used to promote wound healing by using suction to drain excess fluid from wounds. A systematic literature review was undertaken to assess the effectiveness, safety and cost-effectiveness of NPWT for the treatment of chronic wounds. Medline, Embase, CENTRAL, CINAHL and the Coch...

journal_title：Medicina clinica

authors： Trujillo-Martín M,García-Pérez L,Serrano-Aguilar P

更新日期：2011-09-17 00:00:00

abstract：UNLABELLED:BACKGROUND AND OJECTIVE: Tobacco attributable mortality offers a complementary view to smoking prevalence, giving an estimate of its impact at population level. The purpose of this study is to measure the impact, using mortality figures, of tobacco consumption in the Galician population over 34 years from 19...

journal_title：Medicina clinica

authors： Pérez-Ríos M,Santiago-Pérez MI,Cerdeira-Caramés S,Alonso B,Seoane B,Malvar-Pintos A,Hervada-Vidal X

更新日期：2011-09-10 00:00:00

abstract：:Transfer factor (TF) consists of messenger peptides produced by activated T lymphocytes as part of cellular immunity, and it acts in virgin lymphocytes through TF inducers, suppressors and specific antigens. TF is not immunogenic because it is not species-specific, since it contains a consensus sequence of amino acids...

journal_title：Medicina clinica

authors： Sánchez-González DJ,Sosa-Luna CA,Vásquez-Moctezuma I

更新日期：2011-09-10 00:00:00

abstract：:Gaucher's disease (GD) is an inherited metabolic disease due to lack of activity of the enzyme betaglucocerebrosidase. The diagnosis of GD is usually performed by fluorimetric analysis of the enzyme betaglucocerebrosidase. It can also be done by measuring the activity of tandem mass spectrometry. This enzyme can be an...

journal_title：Medicina clinica

authors： Gort L,Coll MJ

更新日期：2011-09-01 00:00:00

abstract：:Calcified aortic valve disease (CAVD) is a prevalent condition, affecting 25% of people older than 65 years. CAVD and atherosclerosis share common risk factors and pathogenic mechanisms. Nevertheless, they present different pathologic lesions. The main factors involved in the pathogenesis of CAVD are genetic predispos...

journal_title：Medicina clinica

authors： Toro R,Mangas A,Gómez F

更新日期：2011-05-14 00:00:00

abstract：:We performed a systematic review to assess the efficacy and safety of extracorporeal albumin dialysis systems in patients with liver failure. After screening 436 references, 10 controlled trials were detected. The analyzed interventions were MARS, Prometheus and Biologic-DT. Efficacy was proven by a reduction in bilir...

journal_title：Medicina clinica

authors： Lafuente S,Bertran MJ,Escorsell A

更新日期：2011-04-23 00:00:00

abstract：BACKGROUND AND OBJECTIVES:To evaluate the association between high levels of glycemia and low serum uric acid levels in two independent population-based samples. PATIENTS AND METHODS:The first sample was taken from the Pizarra Study, a population-based prospective study of 1.226 persons classified according to their g...

journal_title：Medicina clinica

authors： García-Escobar E,Pérez-Valero V,Maseda D,Valdés S,Yahyaoui R,Hernando V,Vicioso MI,Ruiz de Adana MS,Espinosa Rodrı'guez M,Rojo-Martínez G,Soriguer F

更新日期：2011-04-23 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To evaluate the risk factors of complications in lower limbs in diabetic patients. PATIENTS AND METHODS:We evaluated 270 patients with diabetes followed in Hospital la Paz from 2000 to 2008.We measured the ankle-brachial index (ABI), toe-brachial index (TBII), and toe blood pressure (BP). We d...

journal_title：Medicina clinica

authors： Fuentes MM,Herranz de la Morena L,Borge VM,Saez de Ibarra L,Duque MA,Sánchez LF

更新日期：2011-04-09 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Autoimmune diseases/autoantibodies tend sometimes to cumulate in the same individual, probably as a consequence of defects in immune regulation with breakdown of self-tolerance. Autoimmune hepatitis and microscopic polyangiitis have been occasionally reported with other autoimmune diseases, but...

journal_title：Medicina clinica

authors： Prieto-González S,Cardellach F,Estruch R,Miquel R,Grau JM,Cid MC

更新日期：2011-03-26 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To establish the seroprevalence of infection by Borrelia burgdorferi in Navarre (Spain). PATIENTS AND METHOD:Serum samples of 1,429 individuals considered representative of the population of Navarre were analyzed. The individuals were recruited from a list issued by the government of Navarre. ...

journal_title：Medicina clinica

authors： Oteiza-Olaso J,Tiberio-López G,Martínez de Artola V,Belzunegui-Otano T

更新日期：2011-03-26 00:00:00

abstract：:Obesity is an ever-increasing disease in our environment, and a major risk factor for the development of other chronic diseases that increase morbidity and mortality. Bariatric surgery is an effective treatment for obesity, since it not only allows a significant and sustained loss of weight, but also an important redu...

journal_title：Medicina clinica

authors： Ruiz-Esquide V,Peris P,Gifre L,Guañabens N

更新日期：2011-02-26 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Although smoking habit is a well-known cardiovascular risk factor, it has been described that smokers admitted because of myocardial infarction have better prognosis than non smoker patients, which is known as "the smoking paradox". The purpose of our work is to investigate whether this phenome...

journal_title：Medicina clinica

authors： Amor-Salamanca A,Devesa-Cordero C,Cuesta-Díaz A,Carballo-López MC,Fernández-Ortiz A,García-Rubira JC

更新日期：2011-02-19 00:00:00

abstract：:Cystatin C (CysC) is an antiprotease useful for measuring kidney function. Beyond such property, it carries significant prognostic information in several fields of cardiovascular diseases. We review data that support CysC as a prognostic factor in cardiovascular diseases among healthy elderly, hypertensive and heart f...

journal_title：Medicina clinica

authors： Pérez-Calvo JI,Morales Rull JL,Ruiz Ruiz FJ

更新日期：2011-02-19 00:00:00

abstract：BACKGROUND AND OBJECTIVE:This study estimates smoking-attributable mortality in Spain in 2006. POPULATION AND METHOD:Source data included 1) smoking prevalence in Spain; 2) deaths occurred in Spain; and 3) relative risks of mortality by tobacco-caused diseases drawn from the Cancer Prevention Study II. All data corres...

journal_title：Medicina clinica

authors： Banegas JR,Díez-Gañán L,Bañuelos-Marco B,González-Enríquez J,Villar-Álvarez F,Martín-Moreno JM,Córdoba-García R,Pérez-Trullén A,Jiménez-Ruiz C

更新日期：2011-02-12 00:00:00

abstract：BACKGROUND AND OBJECTIVES:To analyze predictor factors of extended-spectrum betalactamasa (ESBL)-producing E. coli and its repercussion in mortality. PATIENTS AND METHODS:Observational and comparative study of a cohort of non-paediatric admitted patients with E. coli bacteraemia (EB). RESULTS:153 EB (22% ESBL-produci...

journal_title：Medicina clinica

authors： García Hernández A,García-Vázquez E,Gómez Gómez J,Canteras M,Hernandez-Torres A,Ruiz Gómez J

更新日期：2011-01-29 00:00:00

abstract：:Autoinflammatory syndromes are characterised by recurrent or persistent inflammation with no increase in the antibody titers or antigen-specific T lymphocytes, and absence of infection. Initially, they included the hereditary periodic fever syndromes, a group of innate immune system monogenic diseases characterised by...

journal_title：Medicina clinica

authors： Antón J

更新日期：2011-01-01 00:00:00

abstract：:During the last few years, insufficient efficacy of currently recommended antimicrobial agents has been observed, mainly in the case of glycopeptides, during the treatment of infections due to methicillin-resistant Staphylococcus aureus, even if these isolates show MIC values within the susceptible range. The phenomen...

journal_title：Medicina clinica

authors： Morosini MI,Cantón R

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVE:Fibromyalgia (FM) is a chronic pain syndrome of unknown etiology, which affects predominantly women. Among the alterations that have been implicated in the pathophysiology of FM, there have been postulated disturbances in serotonin levels and metabolism, and their implication in symptoms. The aim of the prese...

journal_title：Medicina clinica

authors： Cordero MD,Alcocer-Gómez E,Cano-García FJ,de Miguel M,Sánchez-Alcázar JA,Moreno Fernández AM

更新日期：2010-11-13 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To study an outbreak of nosocomial colonisation/infection due to multidrug and carbapenem resistant A. baumannii (ABMDR-C). PATIENTS AND METHODS:Prospective study of patients with ABMDR-C colonisation/infection (January 2007-June 2008). Epidemiological and clinical variables and predictors of ...

journal_title：Medicina clinica

authors： Hernández-Torres A,García-Vázquez E,Gómez J,Canteras M,Ruiz J,Fernández-Rufete A,Herreroa JA,Yagüe G

更新日期：2010-09-18 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Fabry disease is a hereditary disorder. Clinical manifestations are multisystemic. The majority of the patients remain undiagnosed until late in life, when alterations could be irreversible. Early detection of cardiac symptoms is of major interest in Fabry's disease (FD) in order to gain acces...

journal_title：Medicina clinica

authors： Serra VM,Barba MA,Torrá R,Pérez De Isla L,López M,Calli A,Feltes G,Torras J,Valverde V,Zamorano JL

更新日期：2010-09-04 00:00:00

abstract：:The aim of this article is to discuss the implications of the results obtained in the latest large-scale clinical trials designed to evaluate the effect of intensive glycemic control on the vascular complications associated with type 2 diabetes mellitus. The current scientific evidence is reviewed and the implications...

journal_title：Medicina clinica

authors： Mauricio D,Rius F

更新日期：2010-09-01 00:00:00

abstract：:The prevalence of anorexia nervosa has increased in recent years and a large proportion of patients with this disorder have low bone density at diagnosis and, therefore, an increased risk of early and late fractures. The mechanism of bone loss in anorexia nervosa is not well understood, yet it likely includes hypogona...

journal_title：Medicina clinica

authors： Fernández Soto ML,González Jiménez A,Varsavsky M

更新日期：2010-07-17 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Promoting a safety culture in intensive care units (ICUs) is a basic strategy to improve patient safety. The aim of this study was to measure the safety culture in Spanish ICUs. METHOD:We drafted a questionnaire based on the Safety Climate Survey (SCS) and the Safety Attitude Questionnaire-ICU...

journal_title：Medicina clinica

authors： Gutiérrez-Cía I,de Cos PM,Juan AY,Obón-Azuara B,Alonso-Ovies Á,Martin-Delgado MC,Álvarez-Rodríguez J,Aibar-Remón C

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Familial adenomatous polyposis is an inherited disorder characterized by the presence of multiple colorectal adenomas (more than 100 in the classic form and between 10 and 100 in the attenuated one), with a high risk of colorectal cancer development. To improve the diagnostic and therapeutic m...

journal_title：Medicina clinica

authors： Alfaro I,Ocaña T,Castells A,Cordero C,Ponce M,Ramón Y Cajal T,Andreu M,Bujanda L,Herráiz M,Hervás Molina AJ,Fernández-Bañares F,Riestra-Menéndez S,Gargallo C,Ruiz A,Bustamante M,Blanco I,Martínez de Juan F,Registro Espa

更新日期：2010-06-19 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The Chronic Kidney Disease Epidemiology Collaboration (CDK-EPI) equation has been proposed as a replacement for the Modification of Diet in Renal Disease (MDRD) equation to estimate the glomerular filtration rate, but this equation has not yet been evaluated in the general population. PATIENTS...

journal_title：Medicina clinica

authors： López-Suárez A,Beltrán-Robles M,Elvira-González J,Fernández-Palacín F,Bascuñana-Quirell A,Benítez-Del-Castillo J,Gómez-Fernández P

更新日期：2010-05-15 00:00:00

abstract：:Diabetic dyslipidemia, characterized by the lipid triad (elevated plasma triglycerides, low HDL cholesterol and predominance of small, dense LDL particles), is a significant contributor to the elevated cardiovascular risk of type 2 diabetic patients. Statin monotherapy has shown, in different prospective trials, signi...

journal_title：Medicina clinica

authors： Carmena R,Ascaso JF

更新日期：2010-04-03 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Many countries have developed screening programs for CH that bring about a normal somatic and psychological development. The aim of this study is to evaluate the evolution of cases detected by the screening program of congenital hypothyroidism in Catalonia. PATIENTS AND METHODS:The was a descr...

journal_title：Medicina clinica

authors： Gibert Agulló A,Vicens-Calvet E,Carrascosa Lezcano A,Bargadá Esteve M,Potau Vilalta N

更新日期：2010-03-13 00:00:00

abstract：:The health information system in Catalonia has experienced an important evolution but obtaining integrated data to evaluate the health services is still difficult. At the end of 2008 the basis of the information system of the "Center of Results" and a first set of indicators has been approved by the health system stak...

journal_title：Medicina clinica

authors： Argenter-Giralt M,Barba-Albós G,Román-Martínez A

更新日期：2010-02-01 00:00:00

abstract：:The follow-up of the Mediterranean Diet (MD) has been associated with lower mortality and morbidity from cardiovascular diseases. However, it is important to evaluate the scientific evidence provided by published articles. Therefore, in order to analyze the literature on the overall effects of MD on intermediate and f...

journal_title：Medicina clinica

authors： Sotos-Prieto M,Zulet MA,Corella D

更新日期：2010-01-23 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Hypertension is highly prevalent in the very elderly. We studied control rates of hypertension according to clinic blood pressure (BP) and ambulatory BP monitoring (ABPM) in treated hypertensives aged > or =80 years. PATIENTS AND METHOD:Data came from the Spanish Society of Hypertension ABPM R...

journal_title：Medicina clinica

authors： Llisterri JL,Alonso FJ,Gorostidi M,Sierra C,de La Sierra A,Banegas JR,Segura J,Sobrino J,De La Cruz JJ,Madruga F,Aranda P,Redon J,Ruilope LM,en representación de los investigadores del Proyecto CARDIORISC-MAPAPRES. Sociedad Esp

更新日期：2009-11-28 00:00:00

abstract：:Bacterial vaginosis is a widely spread health problem with multiple connotations. It has been the subject of many studies and work during decades and it still remains a polemic entity, with contradictory finding. The polymicrobian etiology, unsolved epidemiology, obstetrico-gynecological complications and high recurre...

journal_title：Medicina clinica

authors： Jesús De La Calle I,Jesús De La Calle MA

更新日期：2009-11-28 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The B-type natriuretic peptide (BNP) has recently emerged as a prognostic marker in acute coronary syndromes (ACS). This role is based on results from randomized trials and other high selected population studies. The aim of this study was to determine the prognostic value of BNP in unselected p...

journal_title：Medicina clinica

authors： Molina-Mora MJ,Cabrera-Bueno F,Jiménez-Navarro M,Linde-Estrella A,García-Pinilla JM,Teresa-Galván Ed

更新日期：2009-10-24 00:00:00

abstract：BACKGROUND AND OBJECTIVE:There is a bidirectional association between neoplasia and venous thromboembolism (VTE). However, whether this association has an impact in tumor recurrence is unknown. The aim of the study is to assess the incidence of cancer recurrence after diagnosis of VTE and determine if VTE could be a ma...

journal_title：Medicina clinica

authors： Blanch Alerany M,Calvo Campos M,Romera Villegas A,Pérez-Piqueras Gómez A,Riera Batalla S,Cairols Castellote MA

更新日期：2009-10-17 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Medulloblastoma is the more frequent malignant cerebral tumor in childhood. PATIENTS AND METHODS:This is an observational study of a retrospective cohort in which there were included all the patients diagnosed of medulloblastoma in the last 19 years (1989-2007) in Hospital de Cruces of Baracal...

journal_title：Medicina clinica

authors： García Casales Z,Echebarría Barona A,Urberuaga Pascual A,Astigarraga Aguirre I,Burgos Bretones JJ,Navajas Gutiérrez A

更新日期：2009-10-03 00:00:00

abstract：BACKGROUND AND OBJECTIVES:To evaluate anti-IgE (ie, omalizumab) efficacy on severe allergic asthma in order to achieve the efficacy of this treatment on severe allergic asthma progress by means of asthma control questionnaire (ACQ), asthma quality of life questionnaire (AQLQ) as well as pulmonary function (FEV1) and ph...

journal_title：Medicina clinica

authors： Pacheco-Galván A,Hinojosa-Macías M,Hurtado-Barbudo B,González-Cervera J,Sueiro-Bendito A

更新日期：2009-10-03 00:00:00

abstract：BACKGROUND:In 2001 an outbreak of Legionnaires' diseases occurred in Murcia, Spain, with one of the lowest known rates of associated mortality. We describe the clinical data of a subgroup of patients, and present the results from molecular and virulence studies to correlate the lower mortality of the overall series wit...

journal_title：Medicina clinica

authors： Gómez J,Mòdol J,García-Núñez M,Baños V,Lorenzo M,Pedro-Botet ML,Hernández T,Herrero JA,Ruiz J,Sabrià M

更新日期：2009-09-12 00:00:00

abstract：:Clinical trials and prospective observational registries are useful methods to gain knowledge of vascular disease. Because the design of clinical trials is mainly based on demonstrating the efficiency of therapeutic procedures, these studies cannot be widely generalized, especially in complex multifactorial diseases s...

journal_title：Medicina clinica

authors： Castillo J,Blanco M

更新日期：2009-09-01 00:00:00

abstract：:The REACH registry allows the degree of control of risk factors associated with atherothrombosis to be evaluated. Although 90% were taking at least one antihypertensive agent, hypertension was controlled in only 42.9% of the patients with vascular disease. This inadequate control may have multiple causes but the main ...

journal_title：Medicina clinica

authors： Gómez Cerezo JF

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:We aimed to assess the population-based incidence and survival of primary Merkel cell carcinoma. MATERIAL AND METHOD:From January 1995 to December 2005, 19 patients diagnosed with primary Merkel cell carcinoma were recruited in the population-based Cancer Registry of Girona. RESULTS:The age-a...

journal_title：Medicina clinica

authors： Vilar-Coromina N,Pérez Bueno F,Alsina Maqueda M,Vilardell Gil L,Izquierdo Font A,Marcos-Gragera R

更新日期：2009-05-16 00:00:00